In order to comprehensively improve the quality of “made in China”，maintain a good order of import and export，as the inspection and quarantine organ of the import and export commodity quality supervision department，it will severely crack down on the counterfeit and shoddy behavior according to the general requirements of the national quality strategic policy. This report，starting from the practice of the Shenzhen inspection and Quarantine Bureau at the port anti-counterfeiting，reviews and summarizes the work of the Bureau in recent years，discusses the problems and difficulties of the current inspection and quarantine work at the port of inspection and quarantine，and makes a preliminary probe into how to build a better port for anti-counterfeiting mechanism so as to play the Department of inspection and quarantine's good role in the field of export and anti-counterfeiting.