Recently，further encouraging the innovation and entrepreneurship has laid a solid foundation for Henan to turn into a strong province with high quality. Meanwhile，Henan's innovation and entrepreneurship has also become a powerful driving force for building a high-quality strong province. However，the current development of Henan's innovation and entrepreneurship is still limited by weak technological innovation ability，lack of institutional innovation and low level of original innovation. Therefore，it is necessary to take more steps to strengthen talent support，improve institutional mechanism and develop environment.