Science and technology finance is an important part of the national science and technology innovation system and financial system. The development of science and technology finance facing small and medium-sized science and technology enterprises is an effective way to promote “mass entrepreneurship and innovation” and realize industrial transformation and upgrading，and it is an important measure to consolidate the foundation of overturn innovation and achieve continuous innovation. Nanshan District has gathered numerous high-quality scientific and technological innovation resources and has the inherent advantages of developing science and technology finance. Nanshan District upholds the idea of “government guidance and marketization operation” and builds a scientific and technological financial ecosystem characterized by “one platform，one system，three linkages，and eight products”. Further improve the online platform for science and technology finance，optimize the operational mechanism of science and technology finance，cultivate talents in science and technology finance，develop intermediaries for scientific and technological finance，create a “government-led，open，market-oriented investment and financing platform”，It could make better use of the supporting role of science and technology finance for technological innovation and form a long-term effective mechanism that closely matches technology and finance.