The three dimensional map of “innovation capability，innovation trend and economic development level” reveals the development rule of science and technology industry innovation center. It shows that the evolution of the world’s science and technology innovation center is divided into four stages：the seed cultivation stage，the emerging catch-up stage，the high-end lead stage，and the rigid decline stage. Now Shenzhen has entered the mid-term of the emerging catch-up stage and is moving towards the high-end lead stage. Shenzhen could adopt the way of development of “internal and external distances，two balances” to create an international science and technology innovation center. The “internal and external distances”：First，to achieve regional integration of innovation in domestic；Second，to realize the internationalization of research and innovation in the world；Third，to focus on improving the efficiency of innovation factors in the future；Fourth，to promote the gathering of international innovation factors in the short term. The “two balances”：First，to balance overtaking innovation and overturn innovation resource allocation；Second，to balance strategic resource allocation between technology centers and financial centers.