In recent years，the development of life sciences and biotechnologyis changing rapidly in the world，especially in China. The basic research of omics，artificial intelligence，structural biology and other technology has made great progress，which has reaching significance for the prevention and treatment of human diseases. The advance on life sciences and biotechnology not only provide the basic support for health management，but also opened a new era and development prospects of health management. Base on these progresses，it’s starting a trend from the traditional risk factor screening to the direction shift of the precision prediction，early warning and intervention. More important，it’s provides new solutions to solve the health problems in grim situation of chronic disease in China.