Based on in-depth interviews with 11 teenagers who suffered from depression in psychiatric units of a hospital in Kunming，this study finds three dimensions of parent-child relationships including emotion，power and interpersonal.First of all，this study aims to discuss the internal and external impact of parent-child relationships on the youth's perspectives.The analysis focuses on the growth of adolescent individuals，the formation of their interpersonal relationships and the social transformation.Secondly，the study analyzes main causes of adolescent depression，including individual imperfection of one's character，less active interactions between child and parents，the student and teachers，their peers as well as the influence of social transformation.Hence，the key concept of “multi-loss”is proposed through this study.It means the loss of love in growth，the self-esteem in personal relationships，the values of life in social reform，and energy in physiological functions，etc.This study also discusses the relations between parent-child relationships and adolescent depression.It shows that while poor relationships cause the disease，the depression also improves the relationships.Finally，the study offers valuable suggestions for the prevention and rehabilitation of depression from the perspective of social work.