School bullying is a worldwide problem. It has attracted the public and government’s attention recently，however，there is a lack of evidence-based study. This paper uses a representative national data collected by the School Safety Research Committee of the China Emergency Management Association in 2016，to explore the association between school bullying and adolescent’s health-related quality of life，deviance behavior（school absence，smoking，alcohol use，physical fighting，and online game addiction），and suicide. The results demonstrate that bullying experience，no matter as a victim or perpetrator，could negatively affect the adolescent’s quality of life，increasing their likelihood of having most of the deviance behavior and their probability of suicide. In some dimensions，cyberbullying has larger effect than the traditional bullying. This paper ends with a discussion of potential policy implementation and future research directions.