Guizhou，one of the most deep poverty-struck western province，is taken as a case example of campaign against poverty in recent years. Relying on continuous and successive poverty alleviation experiments，Guizhou ininitated a Grand Poverty Alleviation Strategy since the end of 2015，when the central government called for a countrywide campaign against poverty then. This report summarizes the progress of poverty alleviation actions in Guizhou under the framework of Grand Poverty Alleviation in six aspects，and concludes five points which could be learned by other provinces in their work of poverty alleviation.