According to the researches on the technological innovation and economic growth，this article constructed a correlation model to verify the relevance between technological innovation and economic growth with the method of linear regression. With standardized mean of technological innovation and per Capita GDP as observed variables of technological innovation and economic growth respectively，we investigated the differences of technological innovation and economic growth in the five western provinces from 2009 to 2013. It comes to the conclusion as follows：technological innovation stimulates the greatest contribution to its economic growth in Xinjiang Province，next is Gansu，and the relatively weak one is Shanxi Province.