The digital economy is sweeping over almost all of the world's industries；the new business model is emergingand the traditional industry is also adjusting the existing mode of operation and service.The disruptive changes in the market drive entrepreneurs and researchers to look at business changes and market trends with new perspectives.This paper introduces the trend of five major business changes driven by digital economy；sharing economy，open innovation，cross-border competition，“precision +” mode and win-win business mode.This paper analyzes the best commercial practice under the five changing trends，and finally looks forward to technological changes in the next 5-year evolution of digital economy.