From the theory of Synergetic Development，based on the position of “New Urbanization Demonstration Area in the central and Western China，Open and Cooperative Demonstration Area Inland，the leading zone of Two-type Society Construction” in the Changjiang Middle Reaches Megalopolis. Around the common probelm of three provinces which can not be solved alone，the top design for the mechanism of Synergetic developing in Changjiang Middle Reaches Megalopolis，and put forword the main works to enhance “One Pole and Three Zones” in Hubei hunan and jiangxi.