As the experimental area of “One Country Two Systems”，Macao cooperates closely with Guangzhou in various fields and makes with good progress under the guiding principle of “Framework Agreement on Cooperation between Guangdong and Macao”. In 2016，the Guangzhou-Macao Cooperation relationship has been raised to a new stage under the introduction of “Macao's Five-Year Development Plan （2016-2020）”. Significant achievements were gained in economic and trade，livelihood，entrepreneurial innovation and educational training since the launch of Guangzhou-Macau cooperation mechanism，and cooperation is expected to be deepened in future with opportunities.