The power of economic development is innovation and entrepreneurship. College students，who are active in mind and have a wide range of knowledge，have great potential and enthusiasm in entrepreneurship. After years of exploration and practices，Guangzhou has built up a relatively perfect entrepreneurial security system and accumulated rich practical experience in promoting the development of college students' entrepreneurship. This article tries to analyze the present situation of Guangzhou college students' entrepreneurship policies and find the deficiency of the current security mechanism. At last，in order to provide reference for relevant policies in the field of practice，this article puts forward some countermeasures and suggestion.