The classroom instruction is an important approach of talents cultivation. It is worth exploring and studying on how to reform classroom instruction mode and make it more suitable to the applied talents cultivation. “The Internet+” concept ushers the teaching in colleges and universities into a new era. The reform of the classroom instruction，based on the “The Internet+” concept，can help not only to break through the bottleneck of traditional teaching methods，but also to realize the teaching approach reform，and to improve the teaching quality and efficiency. Therefore，under the “The Internet+” environment，the reform of classroom instruction is inevitable，and can make it to be better applied to talents cultivation.