Sichuan province has made significantly achievements in public health promotion which was benefited from the governmental practices in strengthening prevention as priority，underpin investment，and effective in controlling health-related risk factors in 2015. The progress could be presented in enhancing basic public health service，improving health condition for vulnerable populations infected and affected，effective in reducing prevalence of major disease，and implementing the Patriotic Health Campaign（PHC）. Further challenges have arisen，however，including extended demands in strengthening public health service，developing institutional constructions and infrastructures，and effective in identifying and responding to emerging infectious diseases and chronic diseases. Data presented in the study will be as broad evidence for potentially greatly benefited to support policy development dealing with impact on health publication challenges.