The industrial development is the cornerstone of the comprehensive development of the Zhongyuan urban agglomeration. The industrial development of the Zhongyuan urban agglomeration is well established，but there are still unreasonable industrial structure，low industrial level，homogeneous competition among cities，and weak economic link between cities. Zhongyuan urban agglomeration in accordance with the focus of the development of advanced manufacturing clusters，strategic emerging industry clusters，modern service industry and modern agriculture cluster ideas，the city clear urban function positioning，industrial development direction around the industrial division of labor，play a comparative advantage. The government guides and strengthens the status and role of the central city of Zhengzhou，avoid duplication，duplication，duplication of investment，homogeneity competition and inter-city internal friction，and realize the complementary resources and benefit sharing and common development.