At present, the grim situation of anti-drug work in guizhou complex, facing many problems: the problem of drug intermingled with poverty, drug problem seriously destroy the ecological environment, the traditional drug harm still dominate, new synthetic drug harm, drug active trading market, mainly sporadic drug, drug in long into the stream, full penetration, migrant workers drug addict problems. Guizhou must take xi general secretary "system of governance, governance according to law, comprehensive control, source governance" social security comprehensive management thoughts as the instruction, the integrated use of various means, promote the drug control work informatization, socialization, under the rule of law.