This report system was studied in guizhou province maternal crowd characteristic, maternal HIV epidemic trend and fashion on HIV/AIDS related knowledge about and HIV testing services use, HIV infection and influencing factors of maternal childbearing willing, medical and health institutions at various levels intervention techniques provide and influencing factors of maternal pregnancy, HIV intervention effect and influence factors. The results showed that the province maternal HIV detection rate, pregnancy detection rate from 86.06% in 2011, significantly increased from 31.50% in recent years were 96.99%, 59.02% (P < 0.001), HIV positive detection rate increased from 3.78/4.01 / million (P > 0.05); Confirmed HIV maternal demographic characteristics are nearly three years in 21 ~ 30 years old, the han nationality, junior high school the following culture and marriage for pregnancy is given priority to, the proportion of sexually transmitted infections (stis) rose from 84.85% to 90.59%; The average knowledge of maternal knowledge of HIV/AIDS was only 61.54%, with better use of HIV antibody testing services and 93.77% for HIV testing; The proportion of hiv-positive mothers who had chosen to terminate their pregnancies increased from 7.46% to 26.47 percent in nearly three years, while non-occupational HIV infected mothers preferred to terminate their pregnancies. There were 396 cases of HIV infection with continued pregnancy, less than 50% of antiviral treatment, and no significant improvement in the past three years. Three factors are closely related to the treatment of antivirus in pregnancy and the number of children present, the confirmation of infection, and the period of intervention. The application of series of research results to the practical work, the provincial maternal HIV detection rate up to 96.99% in 2013, reached the national average, basic implementation "every pregnancy will check"; Through integrated intervention technology, maternal and child block mother-to-child transmission of HIV/AIDS in guizhou rate from 7.78% in 2010 (the 7.9%) dropped to 5.48% in 2014 (6.1%), prevention of HIV mother-to-child transmission effect is significant in guizhou. But maternal HIV infection are mainly low degree of culture, poor economic condition of the farmers or migrant workers, maternal HIV infection have a rising trend, more than 90% of the sexually transmitted infection characteristics should be taken at all levels of government attaches great importance to, and should strengthen to the high risk population of HIV/AIDS prevention and control, to reduce the risk of infection among women of reproductive age.