To create midwest science and technology innovation heights of Henan province，is not only the specific requirements of the central decision-making arrangements，but also the strategic of following the economic and social laws，promoting the economy and the four province building，realizaing a comprehensive well-off society and making more effective strategy for the central plains. Creating midwest science and technology innovation heights，Henan has good foundations and environments，but also has many difficulties and problems. To conform the development trend of innovation，should base on improving the platform carrier construction，expanding the body of innovation，highlighting the open innovation，strengthening the institutional mechanisms and so on. Putting the innovation in the core position of the development of the overall situation and making the great efforts to create midwest science and technology innovation heights.