The global economy will enter a deep adjustment period and China is entering a crucial period of a deepen reform in 2017. Opportunities and challenges of economic development coexist. Sichuan’s Southern Economic Zone will have to face not only a complex world economic environment，but also domestic economic downward pressure. However，with the deepening of the new technology revolution and industrial revolution，the implementation of Chengdu-Chongqing economic zone construction and multi-point and multi-polar development strategy，the implementation of green development concept，and the carrying out of supply-side structural reforms，the economy of Sichuan’s Southern Economic Zone will remain a stable growth. Combined with the new normal and the new situation，Sichuan’s Southern Economic Zone should deepen the reform and open wider to the outside world，strengthen the industrial transformation and upgrading，promote the regional integration process，which will finally boost the economy development of this region to a new level.