The eastern coastal areas is densely populated areas in China，as well as the areas with dense population，economy，and the rapid advance of urbanization. Under the quickly global climate change，the extreme high temperature，extreme rainfall，flood，storm surge，sea level rise，seawater intrusion and other natural disasters occur frequently. And the eastern coastal cities will bear the brunt of them. Through the analysis of the “pressure-state-response model”，we could see that the cities in China are still under huge pressure on climate change. Although positive response have made in the urban infrastructure，urban ecological greening system，etc.，it’s difficult for cities in China to adapt to the great challenges of climate change. Especially，the urban greening，infrastructure，urban management still lag behind，which like the blade of moss hanging over the heads of the Chinese cities. Facing the challenges of climate change，cities in China should improve ability to cope with climate change adaptation，from aspects of urban planning，infrastructure，urban greening system，sponge cities，disaster risk management etc. And we should focus on the construction of climate-friendly and climate resilient cities.