Based on content analysis，this study drew 1154 micro-blog items from 10 typical opinion leaders as research samples and explored the social responsibility issues of these opinion leaders from an information production perspective. The research shows that a low level of social responsibility ratings among opinion leaders in their information production processes. In the aspect of information basic attributes，the information quality produced by micro-blog opinion leaders is not high，with particular low indicators in originality，degree，depth，timeliness，reliability，sources. In the aspect of text framework，micro-blog opinion leaders are inclined to emotional expressions rather than rational analysis. This reliance on emotional mobilizations aggravated the spread of irrational public opinions. In the consultation and discussion quality aspect，opinion leaders in general demonstrated a lack of interest towards public events，issues and demands. Massive amount of opinion leaders’ discussions were of self-interest basis，and showed an obvious top-down agenda setting tendency，which weakened the designed public consultation function of micro-blog.