The Tianjin harbor burst with a explode event that damaged so much things and killed so many people，on August 12st，2015. From that time on，the reason and responsibility of this emergency becomes the hot topics in the micro-blog platform，it get into the focus of the internet public opinion that some government department dereliction of duty. Face with the doubt and accountability of public opinion，the government micro-blog sent out the response mechanism，through the communication way of information release，sentimental mobilization，and inter-action answer，responded to the enquire，doubt，and condemn. When the emergencies take place，face with the anti-corruption opinion in the micro-blog，how can the government micro-blog of functional department to reponded to it？And what’s the responsibility of the government micro-blog in the anti-corruption opinion about the emergencies？This paper analysis to the response mechanism and social responsibility of government micro-blog in the anti-corruption opinion about the emergencies with the four dimension that the development situation，subjective responsibility，publish content，and communication effective.