Due to an ageing society combined with the development towards the world centre of tourism and leisure，the Macao SAR government is paying attention to the provision of quality health care. Nurturing and enhancing health care professionals are the prerequisites for quality health care，and the Qualification，Practice and Registration Regime for Health Care Professionals is a significant legal endeavour in enhancing the calibre of health care professionals. Meanwhile，a comprehensive and thorough assessment and planning on the current state of manpower is also indispensable. In terms of manpower，the quantity of doctors is relatively sufficient，whereas there is an absence of local medical school to offer systematic training to doctors along their professional career. On the other hand，nurses face the problem of manpower shortage，while unreasonable formation of teams and limited promotion opportunities undermine the passion of new entrants. The increasing number of fundamental medical programmes offered by local higher education institutions，the planned establishment of specialist medical school，as well as the joint efforts of health，education and social welfare departments demonstrate a huge significance for the provision of quality health care in Macao. This article puts forward three suggestions on the enhancement of health care manpower，namely through expansion of recruitment and nurture of health care professionals，comprehensive talent planning and optimised management，and initiation of positive practice environment.