According to comparative analysis，the scientific and technological view of youths in Guangzhou，Hong Kong and Macao tends to be positive and optimistic. In terms of degree of positive response，Guangzhou ranks first and Hong Kong and Macao come second and third respectively. But for anxiety for negative effects of science and technology，the ranking is Macao，Hong Kong and Guangzhou respectively. The study also discloses that rapid progress in scientific and technological advances formation of positive attitude towards science. Besides，youths in Guangzhou need more information about STSE （science，technology，society and environment） so that they can further know effects of science on society and environmental influence.