Overall，the layout of Cultural and Creative industries in Shanghai like thermal radiation from urban core functional area to surrounding area. According to the status quo of industrial space layout，various districts can be divided into four types，including the core of city，the intermediate zone with long history，the emerging intermediate and peripheral regions and suburbs. Some problems have been found by searching the development of each region，such as over reliance on the industrial radiation from core area，no prominent the features in the local area，lack of the capacity of industrial radiation in the main city of outskirts，non-significant scope economic effect creating from Industrial Parks. Finally，some trends of development are summarized combination of with analysis of the 13th Five-Year Plan of each district.