In an era of globalization and network，people increasingly focus on their own social networking self-efficacy. Based on the literature review，depth interview and formal questionnaire，this study found that the college students’ social networking self-efficacy questionnaire was composed of four factors，which were interpersonal communication，self-disclosure，self-protection and self-control. The questionnaire is reliable and valid enough to be applicable to measure college students’ social networking self-efficacy. The current situation of college students’ social networking self-efficacy was analyzed. The following conclusions were drawn from this study：College students generally have higher social networking self-efficacy. There had significant differences at social networking self-efficacy，and students from towns are significantly higher than students from rural areas. There have significant differences at social networking self-efficacy，and liberal arts students are significantly higher than science college.