With the development of globalization，more and more countries and governments take the attention to international technology transfer transactions. GZ，as the capital of Guangdong province，is the political，economic and cultural center of South China. With the good economic condition and location advantages，more large talent reserves，GZ absolutely can establish the first-class international technology market. In recent years，Guangzhou has reached new highs in technology trading amount. But comparing with Beijing，Shanghai and other cities，it is still a certain distance. What’s more，the existing technology market operation mechanism，including the technology management mechanism，technology intermediary mechanism，risk investment and financing mechanism，technology assessment and consultation mechanism four aspects have some defects，can’t catch up with the demands of the technology market. Guangzhou can to establish a reasonable and effective operating mechanism. In addition，the government should also attach great importance to the construction environment，actively promote the pearl river delta unified technology market system. Setting up a unified technology trading market system and standardize，form effective supervision；actively nurture and support technology intermediary，technology trading service specialization；strengthen the manufacture-learning-research cooperation，encourage and support the trading and transfer of technology achievements.