The “16+1” Cooperation Framework was established at the 2012 China-CEECs Summit which laid the foundation for cooperation between China and the Central and Eastern European countries. In the past four years，the “16+1” Cooperation has yielded remarkable achievements including the gradual enrichment of the industrial cooperation mechanisms，the strengthened investment cooperation，rapidly growing local cooperation and the emerging cooperation with the third parties. Although the “16+1” cooperation mechanism still faces a series of challenges，the prospect is optimistic.