Hospital intangible assets are those long-term non-monetary assets that are gained by hospitals through medical services provision and management of the hospitals. Valuation of these assets plays an increasing important role in the valuation process of hospital investment. Hospital intangible assets include human resource related intangible assets，hospital brand，patents，technology and etc. There are three key methods when valuating these assets：market approach，income approach and cost approach. In practice，comprehensive quantitative analysis method is widely used by investors. Models are developed to systematically analyze the value of hospital intangible assets. In addition，key-element method is also adopted to conduct qualitative analysis on key focused areas. Another method is the brand-value method which valuates associated brand recognition and channel strengths. Key challenges include selection of appropriate benchmark hospitals，systematically analysis of associated value，potential risks associated with the investment and the valuation of hospital soft services.