The development of regional innovation system is of significance for the innovative nation construction in China. The development of innovative city trial work will propel the development of innovation system construction with regional characteristics. The development of regional innovation system in abroad has achieved a resounding success. Through the supporting the R&D main bodies' innovative development, promoting the links in and out of the system, the Daejeon's innovation system construction has made great progress. Guangzhou should learn from Daejeon, and shape its regional innovation system from the perspectives of R&D park planning, high-end R&D resource agglomeration, government function transformation and lab enterprises establishment. <<