Since Eritrea and South Sudan gained their independence respectively in 1993 and 2001，the principle of respecting the existing African national boundaries has become a hot topic for public attention. Considering the current situation，regional secessionist forces within some African countries would possibly become one of the main threats that challenge this principle. Changes of African national boundaries are caused by a variety of factors both inside and outside Africa，and have given rise to a wide range of noticeable influences. With the rapid development of Sino-Africa relations，it is likely that possible changes of African national boundaries would become an unavoidable topic for China in upcoming years.