Water pollution is one of the most serious environmental problems in China. Pollution control has become an urgent task for environmental protection. Based on comparison of Pudong New Area river network water quality findings in 1999 and 2011，analysis of changing trend on water quality during 2000～2014，causes of pollution，and problems on river regulation work was made. The feasible proposals and measures were presented for water environmental protection and provided for decision-making support for government.