Regional market integration is the outstanding feature of Regional integration development. To Urban agglomeration in the middle reach of Yangtze river，the core of market integration is to Catch the opportunity of historical development period，Eliminate all kinds of administrative and market barriers，and Encourage the rational flow of factors and commodities. We Should give full play under the national macroeconomic regulation and control of the basic resources allocation role of the market，deepen reform of the administrative management system，Break through the administrative division system obstacle，Break regional protection and blockade，Efforts to build the integration of regional market system，and Promoting the free flow and optimized resource configuration.