In the article we focus upon the food and drug supervision and inspection information disclosure and have an analysis of the status quo of such information disclosure in our country. On the other hand，the relevant legislations and experience from the United States，European Union，the United Kingdom，Germany，Japan and Hong Kong SAR are studied as well by adopting a comparative approach. Such comparative study covers the topics of the relations between initiative disclosure and disclosure upon request，process disclosure and result disclosure，limited disclosure and non-disclosure as well as the items subject to disclosure and its procedure，and how to balance the State interest and public interest which are protected by information disclosure against the individual interest which is on the contrary protected by non-disclosure. Based upon such studies of food and drug supervision and inspection information disclosure from both home and abroad，we summarize some good experience and practices in the system construction and daily routines.