In line with the “The Outline of the Plan for the Reform and Development of the Pearl River Delta” and “Framework Agreement on Cooperation Between Guangdong and Macau，” The Policy Address of the Macau Special Administrative Region Government for the year 2014 mentioned that the Macau Government Tourist Office （MGTO） will launch a “Tourism Development Master Plan”，in which a long-term strategic planning of Macau as the position of a world tourism and leisure centre would be proposed. To become an international tourism city，Macau inevitably will face a wide range of social issues triggered by tourism and gaming industry development. This article attempts to summarise the social issues emerged from large-scale tourism activities，including the gaming industry as well as the annual Macau Grand Prix，in order to reflect the possible issues that could emerge in the process of building Macau as a world tourism and leisure centre. Of these issues identified，the priority in land use between visitors and local residents，transport and natural resources planning，diversification of industrial development，and the urgency to train up professionals are major concerns. Only through a sustained assessment and response to these social issues could the demands of both citizens and visitors be balanced，and could the community of Macau be adapted to its new position through incremental changes.