In this chapter，three equipment manufacturing enterprises with typical representative significance in enterprise technical innovation are selected to analyze their basic situation，technical innovation situation and technical innovation experience. The three companies are Harbin Electric Corporation，SZ DJI Technology Co.，Ltd. and Shanghai Micro Electronics Equipment Co.，Ltd. Selected representative enterprises in this chapter have introduced many advanced technical innovation tools such as upholding the principle of market-orientation，pay attention to innovation in application fields；upholding dominant business，increase investment in research and development；upholding talent oriented，reserve high-end talents. These enterprises cultivated Chinese equipment manufacturing enterprises particular entrepreneurial spirit and craftsmanship spirit，have provided great guiding significance to the improvement of innovation methods and upgrading of innovation mode of equipment manufacturing enterprises. Forequipment manufacturing enterprises to achieve high quality development，solve the problems of imbalance and inadequacy in the development of the industry has the important reference significance.