Industrial development promotes cities to become the center of economic and social resource allocation. Facing the new development situation，if cities want to further consolidate and enhance their competitiveness and influence，they must closely follow the mission of the times and strengthen urban industrial innovation. In the past ten years，cities in Henan have made remarkable achievements in industrial innovation. They have significantly improved their innovation power and investment，and their innovation effectiveness has also been significantly improved. In the face of the new development stage，new development requirements and new development tasks，different cities in Henan still need to face up to their weaknesses，firmly anchor the “Two Guarantees”，and accelerate industrial innovation development，consolidate urban competitiveness and comprehensive strength，and accelerate high-quality urban development by strengthening the dominant position of enterprises in innovation，strengthening the introduction and cultivation of innovative talents，strengthening the mechanism of diversified investment in innovation，and strengthening the interaction and integration of the industrial chain，innovation chain，supply chain，factor chain and policy chain.