Promoting and optimizing the coordinated development of regional economy has always been an important goal of Guangdong’s development，It is also an important guarantee for Guangdong to strive to lead the country and create new brilliance in the new journey of building a socialist modern country in an all-round way. This article combs the evolution of Guangdong’s coordinated development strategy since the 18th CPC National Congres，analysis the current situation of coordinated development of Guangdong’s regional economy，in view of the existing problems and weaknesses，puts forward countermeasures and suggestions for Guangdong to achieve a higher level and higher quality of coordinated development of regional economy.