In 2021，the total volume of book publishing and sales in Zhejiang showed an overall growth trend. Although the scale of the retail market decreased slightly under the influence of the epidemic，it has rebounded compared with 2020. With the construction of online platforms and the publication of theme content，online and offline dual channels also maintain a sustained growth trend. This report summarizes and analyzes the exploration and practice of Zhejiang in the Centennial theme content publishing，the transformation of digital enabling publishing，deeply cultivating regional characteristics to promote the publication of high-quality content，and carrying out diversified publishing activities and further analyzes its experience and highlights in content publishing，platform construction，copyright output and publishing planning.