For a long time，the employment promotion of the persons with disabilities has been an integral part of the basic public service supply system of the Shanghai Municipal Government，and an important guarantee for promoting economic growth and maintaining social equity and harmony. With the rapid development of Shanghai’s economy and society，under the guidance of the development concept of “equality，participation and sharing” for the persons with disabilities，the employment of the persons with disabilities in Shanghai presents the characteristics of diversification of participants，diversification of responsibility implementation and diversification of employment modes. This report elaborates the employment promotion mechanism for the persons with disabilities from the aspects of theoretical construction，mechanism evolution and practical exploration. In view of the existing problems such as imperfect interaction mechanism of employment promotion subjects and lack of effective mechanism to mobilize the employment enthusiasm of the persons with disabilities，this report proposes to enhance the joint efforts of employment promotion for the persons with disabilities by building a long-term communication mechanism among various subjects. By promoting the development of the persons with disabilities，the employability of the persons with disabilities will be enhanced，and efforts will be made to achieve high-quality employment and integrated employment for the persons with disabilities in new technology，new markets and new formats.