Beijing enterprises are the vanguard and main force of investment in the Belt and Road countries and regions. In the context of the 2021 COVID-19 pandemic，Beijing enterprises’ investment in the Belt and Road countries and regions is facing new changes and needs new ideas. This report takes perspectives of new situation，investment ideas，current situation，problems and countermeasures to analyze Beijing enterprises’ investment along the Belt and Road countries and regions，and also provides typical cases to illustrate and support. The analysis shows that：first，under the serious internal and external situation in 2021，Beijing enterprises’ investment in the Belt and Road countries and regions declines obviously，flows more to Southeast Asia region，focuses more on trade and service industries，is carried out mainly by central enterprises and increasingly by private enterprises in Beijing，and mainly takes the green-field way；second，some Beijing enterprises forged ahead，actively promoted investment projects in new energy，internet and chip industries and achieved some achievements under the epidemic context；finally，Beijing enterprises can explore new investment opportunities in the Belt and Road countries and regions in such areas as health care，green energy，digital economy and agriculture. This report aims to reveal the current situation of Beijing enterprises’ investment in the Belt and Road countries and regions and to provide reference for future cooperation countermeasures.