The development of cultural industries is an important part of the national cultural and economic development strategy，and a key area for the development of new industries，new business forms and new modes in the Guangdong-Hong Kong-Macao Greater Bay Area. The Guangdong-Hong Kong-Macao Greater Bay Area enjoys favorable geographical conditions，a prosperous cultural market，a strong industrial foundation and comprehensive policy support. However，with an eye to the development goal of the world Bay Area，the future development of the Guangdong-Hong Kong-Macao Greater Bay Area still faces problems and dilemmas such as the imperfect coordination mechanism of the three local governments，the lack of world-class industrial clusters，the lack of prominent industrial highlights and the impact of COVID-19 in 2020. In the future development，the Guangdong-Hong Kong-Macao Greater Bay Area needs to coordinate its overall layout，build distinctive cultural brands，promote innovative development of new business forms，and promote digital upgrading of cultural industries.