It is of great significance to accelerate the construction of a modern drug distribution system and provide industrial support for the construction of a new development pattern and the implementation of the Healthy China strategy. In recent years，drug distribution enterprises have grown rapidly，but due to the implementation of the policy of “Volume-Based procurement”，the benefit space of drug logistics has been greatly reduced. The ubiquitous phenomenon of medical institutions in arrears in drug payments increases the operating costs of enterprises，and the contradiction that drug distribution enterprises are in a weak position in the value chain is prominent. From the perspective of the development potential and general trend of the pharmaceutical distribution industry，the concentration will be further improved，the industrial division of labor will be further refined，and the industry’s penetration development，integrated development，and cross-border development will open up new value space. In the next step，pharmaceutical circulation enterprises need to adjust the allocation of strategic resources，attach importance to the relationship between large-scale operation and professional collaboration，expand value-added services，deeply cultivate the regional market，attach importance to format innovation，extend business to the upstream and downstream of the industrial chain，reduce the management level，cooperate with the financial sector，establish an applicable supply chain financial platform，and enhance their market bargaining power.