Taking Shaoxing，Quzhou and Zhuhai as examples，this report analyzes the typical cases of the reform of the inclusive supplementary medical insurance，including financing and insurance，reimbursement expenses，operating expenses and effectiveness. The results showed that the inclusive supplementary medical insurance program did not set the insurance threshold for the elderly and patients with previous diseases，unified the premium amount，coverage and treatment standard，and solved the social welfare objectives with the market-oriented mechanism，so as to achieve seamless connection with the basic medical insurance. This has established a new guarantee to prevent poverty caused by illness，and effectively alleviated the burden of high medical expenses for patients with serious diseases and severe diseases. The project did not increase government financial expenditure，and the overall operation was stable. It actively explores the transformation to “health-centered”，realizes sustainable development，and makes an important step in improving the multi-level medical security system.