Intellectual property protection is an important indicator to measure and evaluate the business environment of a country or region. In the new era，the central and local governments attach unprecedented importance to the protection of intellectual property rights. How to systematically integrate the existing scattered and separate laws and regulations of intellectual property rights，carry out comprehensive legislation of intellectual property rights protection，and provide legal guarantee for comprehensively strengthening the protection of intellectual property rights have become a new hot and difficult issue in the current legislative theory and practice. Shenzhen and Tianjin have explored and tried using the legislative power of the special economic zone and the provincial local legislative power respectively. Based on the background of local comprehensive legislation on intellectual property protection，this paper makes a preliminary discussion on the legislative ideas，content innovation and problems that need to be paid attention to，in order to provide reference for local and future national comprehensive legislation on intellectual property protection.