The year of 2020 marked the 45th anniversary of the establishment of diplomatic relations between China and the EU，and witnessed COVID-19 pandemic raging across the two partners. The new EU leaders are faced with many political，economic and social problems soon after taking office. Focusing on pandemic prevention and control，economic recovery，promoting cooperation，eliminating disputes and increasing consensus，China and the EU launched a series of high-level political interactions，signed the China-EU Geographical Indications Agreement，and completed the negotiation of the EU-China Comprehensive Agreement on Investmenton schedule，which upgraded the quality of bilateral relations and led to the growth of China-EU trade volume. However，under the dual impact of the “Great Changes unseen in a Century” and the pandemic，uncertainties remain in China-EU relations，and the lack of political mutual trust leads to the EU’s suspicion and accusation against China. Looking forward to China-EU relations in 2021，how to enhance political mutual trust，agree on the major bilateral cooperation agenda for the next decade，effectively control disputes，and rationally resolve contradictions should be the focus of Chinese and European leaders.