This report points out that there is a lot room for cooperation between China and CEE countries in the relevant projects by comparing China and CEE countries in the “Big Three” ball games. The achievements and important events in the exchange and cooperation between China and CEE countries since the establishment of the cooperation mechanism in 2012 are reviewed. It also analyzes the important features of bilateral exchanges and cooperation and clarifies the difficulties and shortcomings. Finally，it tries to put forward some suggestions for both sides to further consolidate the foundation of exchange and expand and deepen the scale and content of cooperation in the complex international situation in the post-pandemic era.