The new media of government affairs is an important channel for the party and the government to contact the masses，serve the masses，and unite the masses in the mobile Internet era. This paper mainly studies and analyzes the content characteristics and rules of the official WeChat account of the Beijing Municipal Science and Technology Commission and the Zhongguancun Administrative Committee，“National Science and Technology Innovation Center”，and its effect in science and technology communication，so as to provide a new media background for government new media to face the fierce competition. To better meet the needs of the public，and improve the effect of science and technology communication，put forward feasible suggestions. Science and technology dissemination is not only a civil issue，but also one of the “responsibilities” of government departments. The new media of science and technology government affairs should further strengthen overall planning and coordination，enrich the content and form of expression，strengthen internal and external communication，strengthen the construction of internal all-media talent team and the supplement of external cooperation forces，give full play to the publicity value and service attributes of new media of science and technology government affairs，and continuously improve Its own communication power，guiding power，credibility and influence can better perform service functions.