2021 is the first year of the ‘fourteenth five year plan’，and the trend of improving the quality and efficiency of medical and health system reform is becoming more and more obvious. This year，the reform made significant progress in promoting the high-quality development of public hospitals，promoting the work experience of Sanming medical reform，strengthening the construction of public health service system，and promoting the normalization of centralized drug purchase. The balanced distribution of high-quality medical resources，the reform of medical insurance system，and the development of traditional Chinese medicine also made steady progress. However，the recurrence of the COVID-19 has also had a significant impact on the continuous deepening of the reform. In the new stage of high-quality development，the reform of the medical and health system still needs to continue to make efforts on the road of healthy China，and constantly promote the development of high-quality and efficient integrated medical and health service system.